金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TWEAK/TNFSF12 Long Name: TNF-like and Weak Inducer of Apoptosis Aliases: TNFSF12 Entrez Gene IDs: 8742 (Human); 21944 (Mouse); 360548 (Rat) Background: TWEAK/TNFSF12 TWEAK is a type II transmembrane protein belonging to the TNF superfamily. The extracellular domains of human and mouse TWEAK share 89% amino acid sequence identity. A soluble form of TWEAK is generated from the membrane-associated molecule by proteolytic cleavage after Arg 93, suggesting that TWEAK may have long-range effects. TWEAK is expressed widely in many tissues and cells.