金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IL-36 beta/IL-1F8 Long Name: Interleukin 36 beta/Interleukin 1 Family 8 Aliases: FIL1 eta; IL-1 eta; IL1F8; IL-1H2; IL36B Entrez Gene IDs: 27177 (Human); 69677 (Mouse) Background: IL-36 beta/IL-1F8 Interleukin 36 beta (IL-36 beta), also known as IL-1F8, FIL-1h and IL-1H2, is a member of the IL-1 family of proteins. IL-36 beta is reported to be actively secreted. Cells expressing IL-36 beta include resting and activated monocytes, and B cells. The receptor for IL-36 beta is thought to be a combination of IL-1 Rrp2 and IL-1 RAcP. Recombinant IL-36 beta activates pathways involving NF-kB and MAPK in an IL-1 Rrp2-dependent manner.