金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Akt3 Long Name: v-Akt Murine Thymoma Viral Oncogene Homolog 3 Aliases: PKB gamma; RAC-gamma Entrez Gene IDs: 10000 (Human); 23797 (Mouse) Background: Akt Isoforms Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.