金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Furin Aliases: FUR; PACE; PC; PCSK3; SPC1 Entrez Gene IDs: 5045 (Human); 18550 (Mouse) Background: Proprotein Convertases This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.