金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SLAM/CD150 Long Name: Signaling Lymphocytic Activation Molecule Aliases: CD150; IPO-3; SLAMF1 Entrez Gene IDs: 6504 (Human) Background: SLAM/SLAMF1/CD150 The Signaling Lymphocytic Activation Molecule (SLAM) family of receptor molecules is a subset of the CD2 family of receptors. SLAM proteins function as co-receptors for lymphocyte activation and/or adhesion and mediate tyrosine phosphorylation signals. SLAM receptor expression is mainly restricted to immune cells. SLAM, also known as CD150, is a transmembrane glycoprotein that is upregulated on activated B cells and T cells but downregulated on Th2 polarized cells. SLAM ligation promotes the activation of Th0/Th1 cells, B cells, eosinophils, mast cell, and macrophages. SLAM also functions as a cellular entry receptor for measles virus.