金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TREM-2 Long Name: Triggering Receptor Expressed on Myeloid Cells 2 Entrez Gene IDs: 54209 (Human) Background: TREM Family The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. The receptors are members of the immunoglobulin superfamily, characterized structurally by a single V-set immunoglobulin (Ig) domain and a short cytoplasmic tail. TREMs associate with the DAP12 signal adapter, an immunoreceptor tyrosine-based activation motif- (ITAM)-containing protein that is phosphorylated and transduces signals when activated.