金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Cathepsin F Aliases: CTSF Entrez Gene IDs: 8722 (Human); 56464 (Mouse) Background: Cathepsin F

Cathepsin F (CTSF) is a lysosomal cysteine protease that participates in protein degradation and has been implicated in tumor progression. Cathepsin F is ubiquitously expressed. The propeptide for Cathepsin F has a cystatin-like N-terminal domain, which may be involved in regulating activity. Nuclear Cathepsin F is believed to be required for activation of hepatic stellate cells during liver fibrosis. In addition, mice deficient in Cathepsin F exhibited lysosomal storage defects and progressive neurodegeneration which was similar to the human condition Neuronal Ceroid Lipofuscinosis (NCL).