货号：AB5425

品牌：Merck Millipore

规格：

目录价：￥4352.00

市场价格：￥3699.20

会员价格：￥3481.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Tyrosine Hydroxylase Antibody, phosphoSer19 | AB5425 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Tyrosine Hydroxylase, phosphoSer19. The antibody recognizes a protein of 60 kDa corresponding to TH phosphorylated at Ser19 in lysates of PC-12 cells stimulated by okadaic acid. Depending upon the brain region being studied, protein load and detection methods some higher molecular weight bands may be detected. View All» Epitope: phosphoSer19 View All» Immunogen: Synthetic peptide from the phosphoSer19 of rat Tyrosine Hydroxylase. View All» Modifications: Phosphorylation View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:1,000 Immunocytochemistry: 1:1,000 Immunohistochemistry: 1:1,000 Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Each vial contains approximately 10 mg of affinity-purified antibody in 100 μL of 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/mL BSA and 50% glycerol. View All» Storage Conditions: Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer. View All» UniProt Number: P07101 View All» Entrez Gene Number:

• NM_000360.3

• NM_199292.2

• NM_199293.2
  View All» Gene Symbol:
  • TH

  • TYH

  • EC 1.14.16.2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. View All» UniProt Summary: FUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.COFACTOR: Fe(2+) ion.SIZE: 528 amino acids; 58524 Da TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Tyrosine Hydroxylase Antibody, phosphoSer19 | AB5425 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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