货号：AB5459

品牌：Merck Millipore

规格：100UL

目录价：￥6281.00

市场价格：￥5338.85

会员价格：￥5024.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GABA A Receptor α4 Antibody, C-terminus | AB5459 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: GABA A receptor alpha4 subunit. The apparent molecular mass of the alpha 4 subunit in rat brain membrane fractions is 64 kDa. View All» Epitope: C-terminus View All» Immunogen: MBP fusion protein from the cytosolic loop of rat GABA A receptor alpha4 subunit. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot: 1:1,000 Immunopreciptation: The antibody will immunoprecipitate 8% of all GABA A receptors in sodium dodecyl sulfate extracts of rat forebrains (150 μL) using 20 μg of antibody. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. View All» Storage Conditions: Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer. View All» UniProt Number: P48169 View All» Entrez Gene Number: NM_000809.2 View All» Gene Symbol:
  • GABRA4

  • GABA
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. View All» UniProt Summary: FUNCTION: SwissProt: P48169 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.SIZE: 554 amino acids; 61640 Da SUBUNIT: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P48169 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family. View All» Brand Family: Chemicon View All» Product Name: Anti-GABA A Receptor α4 Antibody, C-terminus | AB5459 View All» Concentration: 0.2 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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