货号：AB5467

品牌：Merck Millipore

规格：50UL

目录价：￥5820.00

市场价格：￥4947.00

会员价格：￥4656.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-AANAT Antibody | AB5467 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes AANAT (Arylalkylamine N-acetyltransferase). The antibody specifically recognizes the phosphorylated N-terminal PKA site of AANAT (pT31) (Ganguly et al. 2005). The antibody reacts with natural and recombinant protein. View All» Immunogen: Synthetic peptide (phosphorylated) corresponding to amino acids near the N-terminous of rat AANAT conjugated to BSA. {Ganguly, S et al, 2005}. View All» Species Reactivity:

• Bovine

• Human

• Rat

• Sheep

• Fish
  View All» Application Notes: Western Blot: 1:10,000-1:20,000 using ECL. Reacts with the ~23 kDa AANAT protein. Some reactivity may also be seen at ~97 kDa. Suggested blocking buffer is PBS with 10% non fat dry milk and 0.2% Tween-20. Suggested dilution buffer is PBS with 1 mg/mL BSA fraction V. Suggested incubation time is overnight at room temperature (~23°C). Optimal working dilutions must be determined by the end user. View All» Control: POSITIVE CONTROL: Night adapted rat pineal gland. Expression is light sensitive; highest levels are obtained from animals at night. View All» Presentation: Liquid rabbit serum containing no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q16613 View All» Entrez Gene Number: NM_001088.1 View All» Gene Symbol:
  • AANAT

  • SNAT

  • AA-NAT

  • EC 2.3.1.87
    View All» Alternate Names: Arylalkylamine N-acetyltransferase; SNAT; Serotonin Acetylase; EC 2.3.1.87 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle. View All» UniProt Summary: FUNCTION: SwissProt: Q16613 # Catalyzes the N-acetylation of serotonin into N- acetylserotonin.SIZE: 207 amino acids; 23344 Da SUBUNIT: Monomer (By similarity).TISSUE SPECIFICITY: Highly expressed in pineal gland and retina.SIMILARITY: SwissProt: Q16613 ## Belongs to the acetyltransferase family. AANAT subfamily. & Contains 1 N-acetyltransferase domain. View All» Brand Family: Chemicon View All» Product Name: Anti-AANAT Antibody | AB5467 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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