货号：AB5469

品牌：Merck Millipore

规格：100UL

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Ductin Antibody | AB5469 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes ductin (the 16 kDa or c' subunit of the V-ATPase). SPECIES REACTIVITY: The immunogen sequence is common to all species (plants to man). The antibody has specifically been tested on flatworm (invertebrate) and frog and chicken embryonic tissues (vertebrate) tissue. View All» Immunogen: Synthetic peptide (100% conserved in all species) cooresponding to amino acids 115 to 126 of human ATP6VOC {gb AAH07389.1}. View All» Species Reactivity:

• Invertebrates

• Vertebrates
  View All» Application Notes: Western Blot: 1:500-1:1,000. Immunocytochemistry: 1:500 Immunohistochemistry: 1:500 Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified. Liquid in 50% glycerol. Contains no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P27449 View All» Entrez Gene Number: NM_001694.2 View All» Gene Symbol:
  • ATP6V0C

  • VATL

  • Vma3

  • ATPL

  • ATP6C

  • ATP6L

  • EC 3.6.3.14
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L. View All» UniProt Summary: FUNCTION: SwissProt: P27449 # Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.SIZE: 155 amino acids; 15736 Da SUBUNIT: V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein; which is present as a hexamer that forms the proton-conducting pore). Interacts with LASS2. Interacts with HTLV-1 accessory protein p12I.SUBCELLULAR LOCATION: Vacuole membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P27449 ## Belongs to the V-ATPase proteolipid subunit family. View All» Brand Family: Chemicon View All» Product Name: Anti-Ductin Antibody | AB5469 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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