货号：AB5475

品牌：Merck Millipore

规格：100UL

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Prox 1 Antibody | AB5475 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Prox1. The antibody is useful for identifying Prox1 expressing cells during the development of many areas of the nervous system including the dorsal spinal cord, ganglionic eminences, thalamus and hippocampus. View All» Epitope: C-terminus View All» Immunogen: Synthetic peptide from the C-terminus of mouse Prox1. View All» Background Information: Prox1, the homolog of Drosophila Prospero, is a homeobox-containing transcription factor that binds and functions as a co-receptor of liver receptor homolog 1 (LRH1/NR5A2). It is a specific marker for lymphatic endothelial cells, as well as hepatoblasts and hepatocytes. Human Prox1 shares 97% amino acid sequence identity with mouse and rat Prox1. View All» Species Reactivity:

• Rat

• Human

• Zebrafish

• Mouse
  View All» Species Reactivity Note: Rat, mouse and zebrafish. The antibody is also expected to react with human. Other species have not been tested. View All» Application Notes: Immunohistochemistry: 1:2,000-1:10,000 with overnight incubation on 4% paraformaldehyde fixed, frozen tissue sections. For embryos immersion fixation is recommended. For older animals perfusion fixation is recommended. Suggested permeabilization solution is 0.1% Triton X100. Suggested blocking buffer is PBS with 0.1% Triton and 10% serum.Immunocytochemistry: A previous lot of this antibody was used on Immunocytochemistry View All» Control: Embryonic brain tissue. View All» Purification Method: Unpurified View All» Presentation: Rabbit serum in 50 % glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q92786 View All» Entrez Gene Number: NM_002763.3 View All» Gene Symbol: PROX1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunocytochemistry

  • Immunohistochemistry
    View All» UniProt Summary: FUNCTION: SwissProt: Q92786 # May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).SIZE: 737 amino acids; 83203 Da SUBCELLULAR LOCATION: Nucleus (Probable).TISSUE SPECIFICITY: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.SIMILARITY: SwissProt: Q92786 ## Belongs to the Prospero homeobox family. & Contains 1 Prospero-type homeobox DNA-binding domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Prox 1 Antibody | AB5475 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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