货号：AB5519

品牌：Merck Millipore

规格：50UL

目录价：￥5249.00

市场价格：￥4461.65

会员价格：￥4199.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Prodynorphin Antibody | AB5519 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: ProDynorphin, rat. View All» Immunogen: Synthetic peptide from rat ProDynorphin. View All» Species Reactivity: Rat View All» Application Notes: Immunohistochemistry: 1:500 Optimal working dilutions must be determined by the end user. APPLICATION NOTES FOR AB5519 IMMUNOHISTOCHEMISTRY Perfusion: 1) Ca2+-free Tyrode's solution followed by 2) paraformaldehyde-picric acid fixative and 3) 10% sucrose in PBS as a cryo-protectant. Tissues were rapidly dissected out and stored overnight in 0.1 M phosphate buffer (pH 7.4) containing 10% sucrose. Slide-mounted tissue sections were incubated with blocking buffer for 1 hour at room temperature. Primary antibody was diluted in blocking buffer to the appropriate working dilution. Blocking buffer was removed and the slides were then incubated at 2-8°C for 18-24 hours with AB5519. After rinsing in PBS 3 times sections were incubated for 60 minutes at room temperature with Cy3-conjugated secondary antibodies. After mounting in a mixture of PBS and glycerol (1:3) containing 0.1% p-phenylenediamine, sections were examined with a Nikon Microphot-SA epifluorescence microscope. View All» Presentation: Affinity purified Guinea pig antibody in PBS containing 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P01213 View All» Entrez Gene Number: NM_024411.2 View All» Gene Symbol:

• PDYN

• MGC26418

• preprodynorphin

• leumorphin

• beta-neoendorphin-dynorphin

• rimorphin

• prodynorphin

• PENKB

• Preprodynorphin

• leu-enkephalin
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» Entrez Gene Summary: The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. View All» UniProt Summary: FUNCTION: SwissProt: P01213 # Leumorphin has a typical opiod activity and may have anti-apoptotic effect (By similarity).SIZE: 254 amino acids; 28385 Da SUBCELLULAR LOCATION: Secreted.PTM: The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.SIMILARITY: SwissProt: P01213 ## Belongs to the opioid neuropeptide precursor family. View All» Brand Family: Chemicon View All» Product Name: Anti-Prodynorphin Antibody | AB5519 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Affinity Purified View All» Host: Guinea Pig View All»
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