货号：AB5547

品牌：Merck Millipore

规格：

目录价：￥3615.00

市场价格：￥3072.75

会员价格：￥2892.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GRIP1 Antibody | AB5547 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: GRIP1 (glutamate receptor-interacting protein 1). View All» Immunogen: Synthetic peptide from rat GRIP1. View All» Species Reactivity: Rat View All» Application Notes: Western blot: 2-5 μg/mL on rat brain lysate. The antibody reacts with the ~135 kD GRIP1 protein. An additional band at ~50-55 kD may also be seen depending on the sample and concentration of antibody used. Western blot: 1-5 μg/mL on human NT2/D1 cell lysate. The antibody reacts with the ~135 kD GRIP1 protein. An additional band at ~37 kD may also be seen depending on the sample and concentration of antibody used. Immunohistochemistry: 1:320 on formalin-fixed, paraffin embedded rat brain section. It is necessary to pretreat the section with heat induced epitope retrieval. Citrate, pH 6.0 is recommended.Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in 0.02M Phosphate buffer with 0.25M NaCl and 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: Q9Y3R0 View All» Entrez Gene Number: NM_021150.1 View All» Gene Symbol:

• GRIP1

• GRIPAP1

• GRASP1

• GRIP

• KIAA1167
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: Q9Y3R0 # May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.SIZE: 1128 amino acids; 122423 Da SUBUNIT: Interacts with EPHA7, EPHB2, KIF5A, KIF5B, KIF5C, GRIA2, GRIA3, GRIPAP1/GRASP1, PPFIA1, PPFIA4, FRAS1, PLCD4, PTPRF and liprins-alpha. Can form homomultimers or heteromultimers with GRIP2. Forms a ternary complex with GRIA2 and CSPG4 (By similarity). Interacts with EFNB1, EFNB3 and the C-terminal tail of PRLHR. Interacts with SLC30A9 (By similarity).SUBCELLULAR LOCATION: Cytoplasmic vesicle. Endoplasmic reticulum. Cell junction, synapse, postsynaptic cell membrane (By similarity). Note=Cytoplasmic and membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in post-synaptic plasma membrane and post-synaptic densities (By similarity).DOMAIN: "SwissProt: Q9Y3R0 PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1 and EPHB2 and with the C-terminus of PPFIA1 and PPFIA4. PDZ 4 and PDZ 5 mediate interaction with the C-terminus of GRIA2 and GRIA3. PDZ 4, PDZ 5 and PDZ 6 mediate homomultimers. PDZ 7 mediates interaction with PDZ domain of GRASP1. PDZ 7 domain binds CSPG4. PDZ 6 mediates interaction with the C-terminus of liprins- alpha. PDZ 1, PDZ 2 and PDZ 3 mediate interaction with the PDZ- binding motif of FRAS1 (By similarity). PDZ 4 and PDZ 5 mediate interaction with PRLHR.SIMILARITY: Contains 7 PDZ (DHR) domains. " View All» Brand Family: Chemicon View All» Product Name: Anti-GRIP1 Antibody | AB5547 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Postsynaptic View All» Format: Affinity Purified View All» Host: Rabbit View All»
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