货号：AB5563

品牌：Merck Millipore

规格：

目录价：￥5183.00

市场价格：￥4405.55

会员价格：￥4146.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GABA A Receptor β3 Antibody | AB5563 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: GABAA receptor beta3 subunit. The apparent molecular mass of 50-53kDa in rat brain membrane fractions. View All» Immunogen: MBP fusion protein from the cytosolic loop of rat GABAA receptor beta3 subunit. View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:1,000. The antibody reacts with the ~50-56 kD protein in rat brain membrane fractions. Immunopreciptation: The antibody will immunoprecipitate 48% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in 10 mM Hepes, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. View All» Storage Conditions: Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer. View All» UniProt Number: P28472 View All» Entrez Gene Number:

• NM_000814.4

• NM_021912.3
  View All» Gene Symbol:
  • GABRB3

  • MGC9051

  • GABA
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described. View All» UniProt Summary: FUNCTION: SwissProt: P28472 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.SIZE: 473 amino acids; 54116 Da SUBUNIT: Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P28472 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family. View All» Brand Family: Chemicon View All» Product Name: Anti-GABA A Receptor β3 Antibody | AB5563 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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