货号：AB5585

品牌：Merck Millipore

规格：1EA

目录价：￥5125.68

市场价格：￥4356.83

会员价格：￥4100.54

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Recoverin Antibody | AB5585 View All» Replaces: AB5431P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes recoverin. View All» Molecular Weight: 26 kDa View All» Immunogen: Recombinant human recoverin. View All» Background Information: Recoverin is a calcium-binding protein expressed in retinal photoreceptors and midget cone bipolar cells. It appears to delay the termination of the phototransduction cascade by blocking the phosphorylation of photoexcited rhodopsin. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Chicken

• Frog
  View All» Species Reactivity Note: Human, rat, mouse, chicken and frog. Other species have not been tested. View All» Application Notes: Western Blot Analysis: 1:1,000-1:5,000 dilution using ECL.Immunohistochemistry: 1:1,000 (2 hours at room temperature or overnight at 2-8ºC) on frozen and paraffin embedded tissue sections. Suggested fixative is 4% paraformaldehyde or 3% paraformaldehyde with 0.1% glutaraldehyde. Suggested permeabilization solution is 0.1% Triton X-100. Suggested blocking buffer is 0.05 M Tris saline, pH 7.4 containing 2.5% BSA, 0.1% triton and 0.05% sodium azide. Optimal working dilutions must be determined by the end user. View All» Control: POSITIVE CONTROL: Recoverin is found in photoreceptors and midget cone bipolar cells in retina and pinealocytes in pineal gland. View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal serum. Contains no preservative. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. View All» UniProt Number: P35243 View All» Entrez Gene Number: NM_002903.2 View All» Gene Symbol:
  • RCVRN

  • Recoverin

  • RCV1
    View All» Alternate Names: Recoverin View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Immunohistochemistry (Paraffin)

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. View All» UniProt Summary: FUNCTION: SwissProt: P35243 # Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.SIZE: 200 amino acids; 23130 Da TISSUE SPECIFICITY: Retina and pineal gland.DISEASE: SwissProt: P35243 # Identified as the antigen in cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.SIMILARITY: SwissProt: P35243 ## Belongs to the recoverin family. & Contains 4 EF-hand domains. MISCELLANEOUS: Binds two calcium ions; one with high affinity, the other with low affinity. View All» Brand Family: Chemicon View All» Product Name: Anti-Recoverin Antibody | AB5585 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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