货号：AB5594-200UL

品牌：Merck Millipore

规格：200UL

目录价：￥9872.00

市场价格：￥8391.20

会员价格：￥7897.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GABA A Receptor α3 Antibody | AB5594-200UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes GABA(A) alpha3. The epitope does not share homology with any other known proteins. SPECIES REACTIVITIES: It is expected that the antibody will also work on human. The epitope is identical in mouse and highly conserved in bovine (14/15). Other species have not been tested. View All» Immunogen: Peptide corresponding to amino acids 1-15 from human GABA(A) alpha3 subunit (Swiss-Prot accession number P34903,residues 29-43 of the precursor). View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:200 using ECL on rat brain membranes. Immunohistochemistry on rat brain sections. Dilutions should be made using a carrier protein such as BSA (1-3%) Optimal working dilutions must be determined by the end user. View All» Control: CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P34903 View All» Entrez Gene Number: NM_000808.3 View All» Gene Symbol:

• GABRA3

• GABA

• MGC33793
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Western Blotting
    View All» Entrez Gene Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. View All» UniProt Summary: FUNCTION: SwissProt: P34903 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.SIZE: 492 amino acids; 55165 Da SUBUNIT: Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P34903 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family. View All» Brand Family: Chemicon View All» Product Name: Anti-GABA A Receptor α3 Antibody | AB5594-200UL View All» Concentration: 60 μg/200 μL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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