货号：AB5695

品牌：Merck Millipore

规格：

目录价：￥4352.00

市场价格：￥3699.20

会员价格：￥3481.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-G Protein β3 subunit Antibody | AB5695 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: GNB3 (G protein beta3 subunit, cone transducin beta subunit) View All» Immunogen: Synthetic peptide from human GNB3. View All» Species Reactivity:

• Bovine

• Human

• Pig
  View All» Application Notes: Western blot: 1:2,000 using ECL. The antibody reacts with proteins of ~35 kDa. Preferred gel percentage is 12%. Suggested blocking buffer is PBS containing 3% non-fat milk. Immunohistochemistry: 1:200 on frozen tissues sections. Suggested permeablization method is 0.1% Triton X-100. Suggested blocking buffer is PBS containing 0.2% BSA, 0.1% Tween 20, 5% normal rabbit serum and 0.1% sodium azide. Optimal working dilutions must be determined by the end user. View All» Control: POSITIVE CONTROL: retina. Staining for GNB3 is porcine retina is specific to cones: intense within outer segments, and in moderate in cone cell bodies and synaptic pedicles. NEGATIVE CONTROL: kidney. View All» Presentation: Rabbit serum. Liquid. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P16520 View All» Entrez Gene Number: NM_002075.2 View All» Gene Symbol:
  • GNB3

  • SG

  • IG
    View All» Alternate Names: GNB3 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. View All» UniProt Summary: FUNCTION: SwissProt: P16520 # Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.SIZE: 340 amino acids; 37221 Da SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.SIMILARITY: SwissProt: P16520 ## Belongs to the WD repeat G protein beta family. & Contains 7 WD repeats. View All» Brand Family: Chemicon View All» Product Name: Anti-G Protein β3 subunit Antibody | AB5695 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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