货号：AB5705

品牌：Merck Millipore

规格：50UL

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Calcitonin Gene Related Protein Antibody | AB5705 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: CGRP (Calcitonin Gene Related Peptide). View All» Immunogen: A 14 amino acid synthetic peptide from rat CGRP I (processed active peptide). The immunogen sequence is identical at 13 of 14 residues between rat/mouse CGRP I and CGRP II. {KDNFVPTNVGSEAF-NH2} View All» Species Reactivity: Rat View All» Application Notes: Immunohistochemistry: 1:500 See Protocol below. Optimal working dilutions must be determined by the end user. AB5705 has been used successfully on perfusion fixed tissue. Perfusion: 1) Ca2+-free Tyrode's solution followed by 2) a paraformaldehyde-picric acid fixative and 3) 10% sucrose in PBS as a cryo-protectant. Tissues were rapidly dissected out and stored overnight in 0.1 M phosphate buffer (pH 7.4) containing 10% sucrose.Slide-mounted tissue sections were incubated with blocking buffer for 1 hour at room temperature. Primary antibody was diluted in blocking buffer to the appropriate working dilution. Blocking buffer was removed and the slides were then incubated at 2-8°C for 18-24 hours with AB5705. After rinsing in PBS 3 times sections were incubated for 60 minutes at room temperature with Cy3-conjugated secondary antibodies. After mounting in a mixture of PBS and glycerol (1:3) containing 0.1% p-phenylenediamine, sections were examined with a Nikon Microphot-SA epifluorescence microscope. View All» Presentation: Purified chicken IgY. Liquid containing 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P01258 View All» Entrez Gene Number:

• NM_001033952.1

• NM_001033953.1

• NM_001741.2
  View All» Gene Symbol:
  • CALCA

  • CGRP-I

  • KC

  • CT

  • CGRP1

  • katacalcin

  • CALC1

  • CGRP

  • MGC126648

  • calcitonin
    View All» Alternate Names: CGRP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» Entrez Gene Summary: Calcitonin is a peptide hormone synthesized by the parafollicular cells of the thyroid. It causes reduction in serum calcium, an effect opposite to that of parathyroid hormone (PTH; MIM 168450).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P01258 # Katacalcin is a potent plasma calcium-lowering peptide.| P06881 # CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.SIZE: 141 amino acids; 15467 Da SUBCELLULAR LOCATION: Secreted.DOMAIN: SwissProt: P01258 SIMILARITY: SwissProt: P01258 ## Belongs to the calcitonin family.| P06881 ## Belongs to the calcitonin family. View All» Brand Family: Chemicon View All» Product Name: Anti-Calcitonin Gene Related Protein Antibody | AB5705 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Purified View All» Host: Chicken View All»
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