货号：AB5818-50UL

品牌：Merck Millipore

规格：1EA

目录价：￥4625.81

市场价格：￥3931.94

会员价格：￥3700.65

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Potassium Channel Kir4.1 Antibody | AB5818-50UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Kir4.1. The epitope does not share homology with any other known proteins. SPECIES REACTIVITIES: The antibody is also expected to work with mouse and human due to sequence homology. Other species have not been tested. View All» Immunogen: CONTROL ANTIGEN: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile distilled water. For negative control, preincubate 1 μg of protein with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. Synthetic peptide corresponding to amino acids 356-375 of rat, mouse or human Kir4.1 (Accession P49655). View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot: 1:200-1:600 using ECL on rat brain membranes or human platelets. Dilutions should be made using a carrier protein such as BSA (1-3%) Optimal working dilutions must be determined by the end user. View All» Control: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile distilled water. For negative control, preincubate 1 μg of protein with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P78508 View All» Entrez Gene Number: NM_002241.3 View All» Gene Symbol:
  • KCNJ10

  • KIR1.2

  • Kir4.1

  • KCNJ13-PEN

  • Kir1.2

  • KIR4.1

  • BIRK-10
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. View All» UniProt Summary: FUNCTION: SwissProt: P78508 # May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).SIZE: 379 amino acids; 42508 Da SUBUNIT: Seems to form heterodimer with Kir5.1/KCNJ16. Interacts with INADL (By similarity).SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P78508 ## Belongs to the inward rectifier-type potassium channel family. View All» Brand Family: Chemicon View All» Product Name: Anti-Potassium Channel Kir4.1 Antibody | AB5818-50UL View All» Concentration: 15 μg/50 μL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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