货号：AB5856-50UL

品牌：Merck Millipore

规格：50UL

目录价：￥5126.00

市场价格：￥4357.10

会员价格：￥4100.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-VAMP-2 Antibody | AB5856-50UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes VAMP-2 (Vesicle-Associated Membrane Protein 2, Synaptobrevin 2). The epitope does not share homology with any other known proteins. SPECIES REACTIVITIES: It is expected that the antibody will also react with human, Macaca multata and bovine due to sequence homology (25/26). Other species have not been tested. View All» Immunogen: GST fusion protein corresponding to a cytoplasmic, N-terminal part of rat or mouse VAMP-2 (Accession numbers Q64357, NP 036795). View All» Species Reactivity:

• Mouse

• Rat
  View All» Application Notes: Western blot: 1:1,000 using ECL on rat brain membranes. Dilutions should be made using a carrier protein such as BSA (1-3%) Optimal working dilutions must be determined by the end user. View All» Control: CONTROL ANTIGEN: Included free of charge with the antibody is 50 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of PBS. For positive control, in Western blot using 20 ng of protein per Minigel lane. For negative control, preincubate 3 μg of fusion protein with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min) View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P63027 View All» Entrez Gene Number: NM_014232.1 View All» Gene Symbol:
  • VAMP2

  • VAMP-2

  • FLJ11460

  • Synaptobrevin-2

  • SYB2
    View All» Alternate Names: Vesicle-Associated Membrane Protein 2; Synaptobrevin 2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. View All» UniProt Summary: FUNCTION: SwissProt: P63027 # Involved in the targeting and/or fusion of transport vesicles to their target membrane.SIZE: 116 amino acids; 12649 Da SUBUNIT: Interacts with VAPA and VAPB.SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Note=Neuronal synaptic vesicles.TISSUE SPECIFICITY: Nervous system and skeletal muscle.SIMILARITY: SwissProt: P63027 ## Belongs to the synaptobrevin family. & Contains 1 v-SNARE coiled-coil homology domain. View All» Brand Family: Chemicon View All» Product Name: Anti-VAMP-2 Antibody | AB5856-50UL View All» Concentration: 50 μg/50 μL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Target / Localization: Presynaptic View All» Format: Affinity Purified View All» Host: Rabbit View All»
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