货号：AB5964

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Choline Acetyltransferase Antibody | AB5964 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Choline Acetyltransferase, human. Does not appear to work on rat or mouse. View All» Immunogen: Fusion protein View All» Species Reactivity: Human View All» Application Notes: Immunoblotting Immunohistochemistry: 1:200 using DAB with nickel enhancement. The antibody has been used successfully on 50μm human medulla sections which were blocked with 3% H2O2 for 30 min, blocked with 10% normal serum (donkey) for 30 min and citrate buffer (pH 3.0) retrieval for 30 min. Optimal working dilutions must be determined by end user. View All» Presentation: Affinity purified immunoglobulin. Liquid. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap. View All» UniProt Number: P28329 View All» Entrez Gene Number:

• NM_020549.3

• NM_020984.2

• NM_020985.2

• NM_020986.2
  View All» Gene Symbol:
  • CHAT

  • ChAT

  • CMS1A2

  • CHOACTase

  • CMS1A

  • EC 2.3.1.6
    View All» Alternate Names: ChAT View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein. View All» UniProt Summary: FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.SIZE: 748 amino acids; 82568 Da DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Choline Acetyltransferase Antibody | AB5964 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Cytoplasmic View All» Format: Affinity Purified View All» Host: Rabbit View All»
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