货号：AB5966

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Choline Transporter Antibody, high affinity | AB5966 View All» Replaces: AB5960 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Choline Transporter, High Affinity (CHT). View All» Epitope: high affinity View All» Immunogen: full length recombinant human CHT fusion protein. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot: 1:1,000 The antibody reacts with a ~70 kDa protein in mouse spinal cord and a doublet of ~70-75 kDa in mouse striatum tissue homogenate samples. Immunohistochemistry: 1:100-1:500 in mouse heart. Optimal working dilutions must be determined by end user. View All» Presentation: Liquid. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: Q9GZV3 View All» Entrez Gene Number: NP_068587 View All» Gene Symbol:
  • SLC5A7

  • CHT

  • CHT1

  • hCHT

  • MGC126299

  • MGC126300
    View All» Alternate Names: CHT, HAChT View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]). View All» UniProt Summary: FUNCTION: Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion-dependent.SIZE: 580 amino acids; 63,204 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Expressed in putamen, spinal cord and medulla. Specific for cholinergic neurons.SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. View All» Brand Family: Chemicon View All» Product Name: Anti-Choline Transporter Antibody, high affinity | AB5966 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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