货号：AB6020

品牌：Merck Millipore

规格：50Ug

目录价：￥5359.00

市场价格：￥4555.15

会员价格：￥4287.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAP4 Antibody | AB6020 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Antibody recognizes the C-terminus of MAP4. View All» Molecular Weight: ~ 220 kDa View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated peptide corresponding to the C-terminus of human MAP4. View All» Background Information: Microtubule-associated protein 4 (MAP4) is a ubiquitous non-neuronal microtubule-associated protein. This protein binds, polymerizes, and stabilizes microtubules and is thought to regulate microtubule dynamics during the cell cycle. p34cdc2 kinase phosphorylation of MAP4 appears to regulate the control of microtubule reorganization at mitosis (Ookata, 1997). View All» Species Reactivity:

• Human

• Mouse

• Rat

• Horse

• Canine

• Bovine
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. Predicted to react with equine, canine, and bovine based upon 100% sequence homology. View All» Application Notes: Western blot (SNAP ID) Analysis: 0.5 µg/mL from a previous lot detected MAP4 in 10 µg of HeLa cell lysate.Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected MAP4 in HeLa, NIH/3T3, and A431 cells. View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western blot in HeLa cell lysate.Western blot Analysis: 0.05 µg/mL of this antibody detected MAP4 in 10 µg of HeLa cell lysate. View All» Purification Method: Protein A purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P27816 View All» Entrez Gene Number: NP_002366 View All» Gene Symbol:
  • MAP4

  • MAP-4
    View All» Alternate Names:
    • microtubule-associated protein 4

    • cdc kinase

    • MAP-4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» Entrez Gene Summary: The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Non-neuronal microtubule-associated protein. Promotes microtubule assembly. SUBUNIT STRUCTURE: Interacts with SEPT2; this interaction impedes tubulin-binding. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR By similarity. Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338. SEQUENCE SIMILARITIES: Contains 4 Tau/MAP repeats. View All» Product Name: Anti-MAP4 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Purified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-158307.htm
        © Merck Millipore代理AB6020 Anti-MAP4 Antibody;store at +2℃ to +8℃，产品报价联系微信jinshanbio