货号：AB6030

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Integrin alpha 10 (ITGA10) Antibody | AB6030 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the extracellular domain of Integrin alpha 10. View All» Molecular Weight: ~127 kDa observed View All» Epitope: Extracellular Domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human Integrin alpha-10. View All» Background Information: Integrins are transmembrane proteins that are involved in interactions cell-to-cell and cell-to-extracellular matrix (ECM) adhesion. Integrins play diverse roles including cell migration, development, wound healing, differentiation, and apoptosis. Integrin alpha 10 subunit (ITGA10), along with integrin beta 1, is thought to be an essential part of a novel collagen type II receptor expressed mainly in chondrocytes and cartilage tissue. View All» Species Reactivity:

• Human

• Pig

• Rhesus Macaque

• Chimpanzee

• Canine

• Primate
  View All» Species Reactivity Note: Demonstrated to react with human. Predicted to react with pig, rhesus monkey, chimpanzee, and canine based on 100% sequence homology. Other homologies: rat (93% sequence homology). View All» Control: SW-1353 cell lysate View All» Quality Assurance: Evaluated by Western Blot in SW-1353 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected integrin alpha10 in 10 µg of SW-1353 cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O75578 View All» Entrez Gene Number: NP_003628 View All» Gene Symbol:
  • PRO827

  • ITGA10
    View All» Alternate Names:
    • Integrin, alpha 10

    • integrin alpha-10
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Summary: Integrins are integral membrane proteins composed of an alpha chain and a beta chain, and are known to participate in cell adhesion as well as cell-surface mediated signalling. The I-domain containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Integrin alpha-10/beta-1 is a receptor for collagen.SUBUNIT STRUCTURE: Heterodimer of an alpha and a beta subunit. Alpha-10 associates with beta-1.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Widely expressed with highest expression in muscle and heart. Found in articular cartilage.DOMAIN: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.SEQUENCE SIMILARITIES: Belongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain. View All» Product Name: Anti-Integrin alpha 10 (ITGA10) View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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