Merck Millipore代理AB6060 Anti-BBIP10 (rabbit polyclonal)

2025-06-27

货号:AB6060

品牌:Merck Millipore

规格:

目录价:¥4118.00

市场价格:¥3500.30

会员价格:¥3294.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-BBIP10 Antibody | AB6060 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~10 kDa observed. Uncharacterized bands may be visible at ~26 and ~80 kDa in some lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human BBIP10. View All» Background Information: BBIP10 is a BBSome that is a highly conserved Bardet-Biedl syndrome (BBS) protein. BBS is characterized by a dysfunction in the cilium that affects the development and homeostasis of a number of organ systems. BBIP10 is found in the primary cilium of ciliated organisms and, unlike other BBSome proteins, BBIP10 is necessary for microtubule polymerization and acetylation. BBIP10 seems to be important for the formation and maintenance of the BBSome complex and have a second function in the cytoplasm to stabilize microtubules. View All» Species Reactivity:

  • Human

  • Mouse

    View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. Other homologies: Rat (92% sequence homology). View All» Control: Jurkat cell lysate View All» Quality Assurance: Evaluated by Western Blot in Jurkat cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected BBIP10 in 10 µg of Jurkat cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: A8MTZ0 View All» Entrez Gene Number: NP_001182234 View All» Gene Symbol:
    • BBIP1

    • BBIP10

    • NCRNA00081

      View All» Alternate Names:
      • BBSome-interacting protein 1

      • BBSome-interacting protein of 10 kDa

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Summary: BBIP10 functions in ciliogenesis and stabilization of cytoplasmic microtubules (Loktev et al., 2008 [PubMed 19081074]).[supplied by OMIM]. View All» UniProt Summary: FUNCTION: Required for primary cilia assembly and BBSome stability. Regulates cytoplasmic microtubule stability and acetylation.SUBUNIT STRUCTURE: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. Interacts with HDAC6.SUBCELLULAR LOCATION: Cell projection › cilium. Cytoplasm. Note: Localizes inside the primary cilium but not at centriolar satellites.SEQUENCE SIMILARITIES: Belongs to the BBIP10 family.CAUTION: Was previously thought to be non-coding and described as "non-protein coding RNA 81", abbreviated NCRNA00081. View All» Product Name: Anti-BBIP10 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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