货号：AB8225

品牌：Merck Millipore

规格：EA

目录价：￥3673.00

市场价格：￥3122.05

会员价格：￥2938.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CIN85 Antibody | AB8225 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody reacts with the 73 kDa CIN85 protein. View All» Molecular Weight: 73 kDa View All» Immunogen: Recombinant protein corresponding to the N-terminus of human CIN85 (aa: 291-400). View All» Background Information: CIN85 belongs to the CIN85/CMS family of adaptor molecules, characterized by containing three SH3 domains, a proline-rich region and a coiled-coil domain. It is also known as Ruk, SETA, SH3KBP1 or Cbl interacting protein. It is a multidomain adaptor protein implicated in Cbl-mediated downregulation of receptor tyrosine kinases (RTKs). Co-immunoprecipitation experiments using mammalian cells revealed that CIN85 directly bound to BLNK through its SH3 domains. These results indicate a potential role of CIN85 in the B cell receptor-mediated signaling pathway. View All» Species Reactivity: Human View All» Application Notes: Optimal working dilutions must be determined by the end user. View All» Control: Jurkat cells lysate View All» Quality Assurance: Routinely evaluated by Western Blot on Jurkat cells lysate. View All» Presentation: Serum containing containing with 0.05% NaN₃. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: Q96B97 View All» Entrez Gene Number: NP_001019837 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Brand Family: Chemicon View All» Product Name: Anti-CIN85 Antibody | AB8225 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μl View All» Format: Serum View All» Host: Rabbit View All»