货号：AB9016

品牌：Merck Millipore

规格：250Ug

目录价：￥5215.00

市场价格：￥4432.75

会员价格：￥4172.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Chx10 Antibody, N-terminus | AB9016 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Chx10 View All» Epitope: N-terminus View All» Immunogen: Recombinant human Chx10 protein, N-terminal. View All» Species Reactivity:

• Bovine

• Human

• Mouse

• Rat
  View All» Application Notes: Immunoblotting: 0.5-1.0 μg/mL. Reacts with the 46 kD protein in rat and mouse retinal tissue lysate. Optimal working dilutions must be determined by the end user. View All» Presentation: Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P58304 View All» Entrez Gene Number: NM_182894.2 View All» Gene Symbol:
  • VSX2

  • HOX10

  • MCOPCB3

  • CHX10

  • MCOP2

  • RET1
    View All» Alternate Names: Hox-10; Ocular Retardation; C. Elegans ceh-10 Homeo Domain Containing Homolog View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: P58304 # Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity).SIZE: 361 amino acids; 39411 Da SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.DISEASE: SwissProt: P58304 # Defects in VSX2 are the cause of microphthalmia with cataracts and iris abnormalities [MIM:610092]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. It is a cause of congenital blindness. & Defects in VSX2 are the cause of isolated microphthalmia with coloboma 3 (MCOPCB3) [MIM:610092]; also known as isolated colobomatous microphthalmia 3. & Defects in VSX2 are the cause of isolated microphthalmia 2 (MCOP2) [MIM:610093]; also known as clinical anophthalmia.SIMILARITY: SwissProt: P58304 ## Belongs to the paired homeobox family. & Contains 1 CVC domain. & Contains 1 homeobox DNA-binding domain. & Contains 1 OAR domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Chx10 Antibody, N-terminus | AB9016 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 250 µg View All» Format: Purified View All» Host: Sheep View All»
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