货号：AB9187

品牌：Merck Millipore

规格：

目录价：￥4469.00

市场价格：￥3798.65

会员价格：￥3575.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Histamine H1 Receptor, pain View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Histamine H1 Receptor. View All» Immunogen: Synthetic peptide from the 2nd extracellular domain of human Histamine H1 Receptor. View All» Species Reactivity: Human View All» Application Notes: Immunohistochemistry on paraffin embedded tissue sections. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide. View All» Storage Conditions: Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P35367 View All» Entrez Gene Number:

• NM_000861.3

• NM_001098211.1

• NM_001098212.1

• NM_001098213.1
  View All» Gene Symbol:
  • HRH1

  • H1-R

  • hisH1
    View All» Sales Restrictions: This product is not available for sale in Japan. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry (Paraffin) View All» Entrez Gene Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. View All» UniProt Summary: FUNCTION: SwissProt: P35367 # In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.SIZE: 487 amino acids; 55784 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.PTM: Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.SIMILARITY: SwissProt: P35367 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Histamine H1 Receptor, pain View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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