货号：AB9480

品牌：Merck Millipore

规格：50Ug

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Retinoic Acid-Induced 3 Antibody | AB9480 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Retinoic Acid-Induced 3 [RAI3/RAIG1]. View All» Immunogen: Synthetic peptide from the 2nd extracellular domain of human Retinoic Acid-Induced 3. View All» Species Reactivity: Human View All» Application Notes: Immunohistochemistry on paraffin embedded tissue sections. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide. View All» Storage Conditions: Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q8NFJ5 View All» Entrez Gene Number: NM_003979.3 View All» Gene Symbol:

• GPRC5A

• RAIG-1

• RAIG1

• RAI3

• GPCR5A
  View All» Alternate Names: RAI3/RAIG1 View All» Sales Restrictions: This product is not available for sale in Japan. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry (Paraffin) View All» Entrez Gene Summary: This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. View All» UniProt Summary: FUNCTION: SwissProt: Q8NFJ5 # Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.SIZE: 357 amino acids; 40251 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.TISSUE SPECIFICITY: Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to Ref.5: expressed at low but detectable level in pancreas and heart.SIMILARITY: SwissProt: Q8NFJ5 ## Belongs to the G-protein coupled receptor 3 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Retinoic Acid-Induced 3 Antibody | AB9480 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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