货号：AB9602

品牌：Merck Millipore

规格：100UL

目录价：￥4592.00

市场价格：￥3903.20

会员价格：￥3673.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Plexin-A1 Antibody | AB9602 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Plexin-A1. The immunogen sequence has low homology with other plexin family members. View All» Immunogen: Synthetic peptide from the semaphorin domain of human plexin-A1. View All» Species Reactivity:

• Human

• Rat
  View All» Application Notes: Western blot: 1:1,000 on neonatal rat brain and COS-7 cells transfected with mouse Plexin-A1. The antibody reacts with the ~220 kDa protein. The suggested antibody diluent is PBS containing 5% non-fat milk and 0.04% Tween 20. Other bands may be present depending on the concentration of antibody and sample used. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS containing 50% glycerol, 1 mg/mL BSA and 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9UIW2 View All» Entrez Gene Number: NM_032242.2 View All» Gene Symbol:
  • PLXNA1

  • NOV

  • PLXN1

  • PLEXIN-A1

  • NOVP
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: SwissProt: Q9UIW2 # Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity).SIZE: 1896 amino acids; 211087 Da SUBUNIT: Interacts directly with NRP1 and NRP2. Interacts with FARP2, RND1 and KDR/VEGFR2. Binding of SEMA3A leads to dissociation of FARP2 (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).TISSUE SPECIFICITY: Detected in fetal brain, lung, liver and kidney.SIMILARITY: SwissProt: Q9UIW2 ## Belongs to the plexin family. & Contains 4 IPT/TIG domains. & Contains 1 Sema domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Plexin-A1 Antibody | AB9602 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Plasma membrane, growth cone View All» Format: Affinity Purified View All» Host: Rabbit View All»
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