货号：AB9604

品牌：Merck Millipore

规格：1EA

目录价：￥4570.85

市场价格：￥3885.22

会员价格：￥3656.68

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Semaphorin 3A Antibody, central region | AB9604 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Semaphorin 3A. The immunogen sequence has low homology with other semaphorin family members. View All» Immunogen: Synthetic peptide from the central region of human semaphorin 3A. View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: It is expected that the antibody will also react with mouse. View All» Application Notes: Western blot: 1:1,000 on neonatal rat brain and recombinant human Semaphorin 3A/Fc chimera (95/125 kDa). The antibody reacts with the ~95 kDa protein. The suggested antibody diluent is PBS containing 5% non-fat milk and 0.04% Tween 20.Optimal working dilutions must be determined by the end user. View All» Presentation: Liquid in PBS containing 50% glycerol, 1 mg/mL BSA and 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q14563 View All» Entrez Gene Number: NM_006080.2 View All» Gene Symbol:
  • SEMA3A

  • SEMAD

  • SEMAIII

  • SEMA1-PEN

  • semaphorin-like

  • MGC133243

  • SEMA1

  • Hsema-I

  • Hsema-III

  • SemD

  • coll-1

  • SEMAL
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. View All» UniProt Summary: FUNCTION: SwissProt: Q14563 # Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1 (By similarity).SIZE: 771 amino acids; 88889 Da SUBCELLULAR LOCATION: Secreted (By similarity).DOMAIN:SwissProt: Q14563 Strong binding to neuropilin is mediated by the carboxy third of the protein.SIMILARITY: Belongs to the semaphorin family. & Contains 1 Ig-like C2-type (immunoglobulin-like) domain. & Contains 1 PSI domain. & Contains 1 Sema domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Semaphorin 3A Antibody, central region | AB9604 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Plasma membrane, growth cone View All» Format: Affinity Purified View All» Host: Rabbit View All»
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