货号：AB9766-200UL

品牌：Merck Millipore

规格：200UL

目录价：￥9823.00

市场价格：￥8349.55

会员价格：￥7858.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Kv12.1 Antibody | AB9766-200UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Kv12.1 (Elk1, KCNH8, ether-a-go-go like K⁺ channel 3, Voltage gated K⁺ channel subfamily H member 8). View All» Immunogen: Purified peptide from amino acids 143-157 of rat Kv12.1 . View All» Species Reactivity:

• Human

• Rat
  View All» Species Reactivity Note: The immunogen sequence is 14 of 15 amino acids identical in mouse. View All» Application Notes: Western blot: 1:200 using ECL on rat cortex lysate. Dilutions should be made using a carrier protein such as BSA (1-3%). Optimal working dilutions must be determined by the end user. View All» Control: Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 µL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9QWS8 View All» Entrez Gene Number: NM_145095 View All» Gene Symbol: ELK1 View All» Alternate Names: Elk1, KCNH8, ether-a-go-go like K⁺ channel 3, Voltage gated K⁺ channel subfamily H member 8 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly.Subunit structure: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.Subcellular location: Membrane; Multi-pass membrane protein.Tissue specificity: Detected in superior cervical, mesenteric and coeliac ganglia. Expressed in brain (piriform cortex, olfactory tubercle, cerebral cortex, hippocampus pyramidial cells and dentate gyrus and basal ganglia of caudate/putamen and accumbens nucleus). Expressed in pituitary.Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.Sequence similarities: Belongs to the potassium channel family. H (Eag) subfamily.Contains 1 cyclic nucleotide-binding domain.Contains 1 PAC (PAS-associated C-terminal) domain.Contains 1 PAS (PER-ARNT-SIM) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Kv12.1 Antibody | AB9766-200UL View All» Concentration: 0.8 mg/mL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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