货号：AB9858

品牌：Merck Millipore

规格：1ea

目录价：￥1295.00

市场价格：￥1100.75

会员价格：￥1036.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GPCR G2A Antibody | AB9858 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes rat GPCR G2A (G protein-coupled receptor G2A View All» Immunogen: Highly purified peptide from C-terminus of rat G2A. View All» Species Reactivity: Rat View All» Application Notes: Immunohistochemistry on formalin fixed, paraffin embedded rat cerebellum. Optimal working dilutions must be determined by the end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity purified immunoglobulin. Liquid in 0.1M Glycine / 0.2M Tris buffer solution pH7.8 containing 0.02% sodium azide. View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: Q9UNW8 View All» Entrez Gene Number: NM_013345.2 View All» Gene Symbol:

• GPR132

• G2A

• MGC99642
  View All» Alternate Names: G protein-coupled receptor G2A View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry (Paraffin) View All» Entrez Gene Summary: This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression. View All» UniProt Summary: FUNCTION: SwissProt: Q9UNW8 # Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication.SIZE: 380 amino acids; 42499 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (Probable). Note=Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity).TISSUE SPECIFICITY: Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.SIMILARITY: SwissProt: Q9UNW8 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-GPCR G2A Antibody | AB9858 View All» Concentration: 100 μg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 25 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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