货号：ABC149

品牌：Merck Millipore

规格：100Ug

目录价：￥5820.00

市场价格：￥4947.00

会员价格：￥4656.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-BST2 Antibody | Cat. No. ABC149 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the extracellular domain of BST2 View All» Molecular Weight: ~33 kDa observed. The calculated molecular weight of this protein is 20 kDa, but can be observed at ~25-35 kDa due to high glycosylation. View All» Epitope: extracellular domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human BST2. View All» Background Information: BST-2 also known as CD317 and Tetherin, bone marrow stromal antigen 2 (BST-2) is an interferon-inducible transmembrane protein that potently inhibits the release of nascent retrovirus particles. BST-2 is downregulated by the viral Vpu protein. BST-2 acts as a direct physical tether, which holds and links virions at the cell membrane. These tethered virons can remain on the cell surface or be internalized by endocytosis for degradation. BST-2 inhibits MMP2 and MMP15 activity, resulting in the attenuation of cellular proliferation and migration. BST-2 interaction with LILRA/ILT7 receptors in plasmacytoid dendritic cells negatively regulates IFN production in response to viral infection. View All» Species Reactivity: Human View All» Application Notes: Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected BST2 in human cardiac myocyte and human hepatocyte tissues. View All» Control: Human bone marrow tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human bone marrow tissue lysate.Western Blot Analysis: 1.0 µg/mL of this antibody detected BST2 in 10 µg of human bone marrow tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q10589 View All» Entrez Gene Number: NP_004326 View All» Gene Symbol: BST2 View All» Alternate Names:

• Bone marrow stromal antigen 2

• BST-2

• HM1.24 antigen

• Tetherin
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunohistochemistry (Paraffin)
    View All» Product Name: Anti-BST2 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-158769.htm
    © Merck Millipore代理ABC149 Anti-BST2 Antibody;store at +2℃ to +8℃，产品报价联系微信jinshanbio