货号：ABC156

品牌：Merck Millipore

规格：100Ug

目录价：￥5039.00

市场价格：￥4283.15

会员价格：￥4031.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-BAG family molecular chaperone regulator 3 (BAG3) Antibody | ABC156 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~74/40 kDa observed. An uncharacterized band may appear at ~65 kDa in some lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human BAG3. View All» Background Information: Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Mouse, Rat, Canine, and Rhesus Macaque based on 100% sequence homology. View All» Application Notes: Immunohistochemistry Analysis: A 1:500-1:1,000 dilution from a representative lot detected BAG3 in human cardiac and renal tissues. View All» Control: DU145 cell lysate View All» Quality Assurance: Evaluated by Western Blot in DU145 cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected BAG3 in 10 µg of DU145 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O95817 View All» Entrez Gene Number: NP_004272 View All» Gene Symbol:

• BAG3

• BIS
  View All» Alternate Names:
  • Bcl-2-associated athanogene 3

  • Bcl-2-binding protein Bis

  • Docking protein CAIR-1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry (Paraffin)
      View All» Product Name: Anti-BAG family molecular chaperone regulator 3 (BAG3) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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