货号：ABC24

品牌：Merck Millipore

规格：

目录价：￥4383.00

市场价格：￥3725.55

会员价格：￥3506.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GATE-16 Antibody | ABC24 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~16 kDa observed View All» Immunogen: KLH-conjugated linear peptide corresponding to human GATE-16. View All» Background Information: GATE-16 (also known as Golgi-associated ATPase Enhancer of 16 kDa, Gamma-aminobutyric acid receptor-associated protein-like 2 or GABARAPL2) is the mammalian homologue of Apg8 ubiquitin-like protein which plays a role in autophagy. GATE-16 has also been associated with intra-Golgi transport and receptor organization. GATE-16 is necessary for the maturation of the autophagosome. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Bovine

• Chimpanzee
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine and Chimpanzee based on 100% sequence homology. View All» Control: Rat brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rat brain tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected GATE-16 in 10 µg of rat brain tissue lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P60520 View All» Entrez Gene Number: NP_009216 View All» Gene Symbol:
  • GABARAPL2

  • FLC3A

  • GEF2
    View All» Alternate Names:
    • Gamma-aminobutyric acid receptor-associated protein-like 2

    • GABA(A) receptor-associated protein-like 2

    • Ganglioside expression factor 2

    • GEF-2

    • General protein transport factor p16

    • Golgi-associated ATPase enhancer of 16 kDa

    • GATE-16

    • MAP1 light chain 3-related protein
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity).SUBUNIT STRUCTURE: Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1. SUBCELLULAR LOCATION: Golgi apparatus (By similarity). TISSUE SPECIFICTY: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SEQUENCE SIMILARITIES: Belongs to the MAP1 LC3 family. View All» Product Name: Anti-GATE-16 Antibody | ABC24 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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