货号：ABC273

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-SLC22A18 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~40 kDa observed. Uncharacterized bands may appear at ~35 kDa and ~39 kDa in some lysates. View All» Immunogen: GST-tagged recombinant protein corresponding to human SLC22A18. View All» Background Information: SLC22A18 is a member of the family of polyspecific organic-cation transporters that localize at the apical membrane surface of renal proximal tubules. SLC22A18 is expressed at high levels in the kidney, liver, colon and in fetal renal proximal tubules and present at lower levels in heart, brain and lung. Defects in SLC22A18 are associated with breast and lung cancer and are the cause of rhabdomyosarcoma type 1, a malignant tumor derived from striated muscle. More recently, SLC22A18 has been shown to function as a tumor suppressor in glioma and represents a candidate biomarker for long-term survival in this disease. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Application Notes: Western Blotting Analysis: A 1:500 dilution from a representative lot detected SLC22A18 in 10 µg of rat brain tissue lysate.Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected SLC22A18 in human liver and colon cancer tissues. View All» Control: Mouse brain tissue lysate View All» Quality Assurance: Evaluated by Western Blotting in mouse brain tissue lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected SLC22A18 in 10 µg of mouse brain tissue lysate. View All» Purification Method: Antigen Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. View All» UniProt Number: Q96BI1 View All» Gene Symbol:
  • SLC22A18

  • BWR1A

  • BWSCR1A

  • HET

  • IMPT1

  • ITM

  • ORCTL2

  • SLC22A1L

  • TSSC5
    View All» Alternate Names:
    • Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein

    • Efflux transporter-like protein

    • Imprinted multi-membrane-spanning polyspecific transporter-related protein 1

    • Organic cation transporter-like protein 2

    • Solute carrier family 22 member 1-like

    • Tumor-suppressing STF cDNA 5 protein

    • Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein

    • p45-Beckwith-Wiedemann region 1 A
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Product Name: Anti-SLC22A18 View All» Concentration: 0.3 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 150 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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