货号：ABC51

品牌：Merck Millipore

规格：

目录价：￥4048.00

市场价格：￥3440.80

会员价格：￥3238.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Kallistatin Antibody | ABC51 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~52 kDa observed. Some uncharacterized bands may be observed at ~22 kDa and ~120 kDa in some tissue lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human Kallistatin. View All» Background Information: Kallistatin is a human tissue kallikrein inhibitor. Kallistatin inhibits human tissue kallikrein's activity toward kininogen and tripeptide substrates, Inhibition is achieved by the formation of a stable inhibitor and enzyme complex, and with the generation of a cleaved C-terminal fragment at the reactive site of kallikrien. Kallistatin may also play a role in certain types of cancer. View All» Species Reactivity:

• Human

• Chimpanzee

• Rhesus Macaque
  View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Chimpanzee and Rhesus Macaque based on 100% sequence homology. Other homologies: Rat (67% sequence homology). View All» Application Notes: Immunohistochemisty Analysis: A 1:500 dilution from a representative lot detected Kallistatin in acini and islets of Langerhans of human pancreatic adenocarcinoma tissue, and in hepatocytes of fatty human liver tissue. View All» Control: Human liver tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human liver tissue lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected Kallistatin in 10 µg of human liver tissue lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P29622 View All» Entrez Gene Number: NP_006206 View All» Gene Symbol:
  • SERPINA4

  • KST

  • PI4
    View All» Alternate Names:
    • Kallistatin

    • Kallikrein inhibitor

    • Peptidase inhibitor 4

    • PI-4

    • Serpin A4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry (Paraffin)
        View All» UniProt Summary: FUNCTION: Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.SUBUNIT STRUCTURE: Monomer and some homodimers.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma. View All» Product Name: Anti-Kallistatin View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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