货号：ABC58

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GABARAP/GABARAPL1 Antibody | ABC58 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes GABA(A) receptor-associated protein-like 1 at the N-terminal of Interaction with GABRG2 domain. View All» Molecular Weight: ~14 kDa observed View All» Epitope: N-terminal of Interaction with GABRG2 domain View All» Immunogen: KLH-conjugated linear peptide corresponding to human GABA(A) receptor-associated protein-like 1 at the N-terminal of Interaction with GABRG2 domain. View All» Background Information: GABA(A) receptor-associated protein-like 1 (GABRAPL1) is a ubiquitin-like modifier with a ubiquitin-like fold that targets lipid membranes instead of proteins. GABA(A) receptor-associated protein-like 1 increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Studies implicate a relationship between the expression of GABA(A) protein-like 1 to cellular growth and breast adenocarcinoma and that level of GABRAPL1 mRNA expression in breast tumor may be a good indicator of the risk of recurrence. View All» Species Reactivity:

• Human

• Mouse

• Rat

• Pig
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Porcine based on 100% sequence homology. View All» Control: Raji cell lysate View All» Quality Assurance: Evaluated by Western Blot in Raji cell lysate.Western Blot Analysis: 0.05 µg/mL of this antibody detected GABA(A) receptor-associated protein-like 1 on 10 µg of Raji cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9H0R8 View All» Entrez Gene Number: NP_113600 View All» Gene Symbol:
  • GABARAPL1

  • GEC1
    View All» Alternate Names:
    • Gamma-aminobutyric acid receptor-associated protein-like 1

    • Early estrogen-regulated protein

    • GABA(A) receptor-associated protein-like 1

    • Glandular epithelial cell protein 1

    • GEC-1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. SUBUNIT STRUCTURE: Interacts with GABRG2 and beta-tubulin (By similarity). Interacts with OPRK1. SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton. Membrane (By similarity). Endoplasmic reticulum (By similarity). Golgi apparatus (By similarity). TISSUE SPECIFICITY: Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. SEQUENCE SIMILARITIES: Belongs to the MAP1 LC3 family. View All» Product Name: Anti-GABA(A) receptor-associated protein-like 1 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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