Merck Millipore代理ABC67 Anti-Mitochondrial fission 1 protein (Fis1) Antibody;抗线粒体分裂1蛋白(Fis1)抗体store at +2℃ to +8℃

2025-06-27

货号:ABC67

品牌:Merck Millipore

规格:100Ug

目录价:¥5513.00

市场价格:¥4686.05

会员价格:¥4410.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Mitochondrial fission 1 protein (Fis1) Antibody | ABC67 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the cytoplasmic topological domain of Mitochondrial fission 1 protein. View All» Molecular Weight: ~17 kDa observed View All» Epitope: Cytoplasmic topological domain View All» Immunogen: KLH-conjugated-linear peptide corresponding to the cytoplasmic topological domain of human Mitochondrial fission 1 protein. View All» Background Information: Mitochondrial fission 1 protein, hFIs1, is an overexpressed mammlian protein that is localized to the outer mitochondrial membrane of various cell types. It is involved in the fragmentation of the mitochondrial network and its perinuclear clustering, resulting in the release of cytochrome c from the mitochondrion, and apopotosis. It is known to mediate peroxisomal fission and also plays a critical role in histone function by demethylating Lys-4 of histone H3. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Other homologies: Rat and Mouse (83% sequence homology). View All» Control: Raji cell lysate View All» Quality Assurance: Evaluated by Western Blot in Raji cell lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Mitochondrial fission 1 protein in 10 µg of Raji cell lysate. View All» Purification Method: Affinity Purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9Y3D6 View All» Entrez Gene Number: NP_057152 View All» Gene Symbol:

  • FIS1

  • TTC11

  • CGI-135

    View All» Alternate Names:
    • FIS1 homolog

    • hFis1

    • Tetratricopeptide repeat protein 11

    • TPR repeat protein 11

      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. View All» UniProt Summary: FUNCTION: Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.SUBUNIT STRUCTURE: Interacts with DNM1L/DLP1 through the TPR region. Interacts with MARCH5.SUBCELLULAR LOCATION: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein. View All» Product Name: Anti-Mitochondrial fission 1 protein (Fis1) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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