货号：ABD37

品牌：Merck Millipore

规格：

目录价：￥4439.00

市场价格：￥3773.15

会员价格：￥3551.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-REM 2 (GTP-binding protein) Antibody | ABD37 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes the C-terminus of REM2. View All» Molecular Weight: ~42 kDa observed. The calculated molecular weight is 37 kDa, however REM2 has been shown as a ~42 kDa band in western blots (Finlin, B., et al. (2000). Biochem. J. 347:223-231.). An uncharacterized band appears at ~62 kDa in some lysates. View All» Epitope: C-terminus View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human REM2. View All» Background Information: The GTP-binding protein REM 2 (REM2) is a member of the RGK subfamily of Ras-like GTPases. REM2 is highly expressed in the brain and may have multiple related effects on neural function. Previous studies have demonstrated that REM2 may play a role in the development of both GABAergic and glutamatergic synapses. It has also been reported that REM2 is required specifically for the maturation of dendritic spines and may affect calcium homeostasis through inhibition of voltage-gated Ca2+ channels. View All» Species Reactivity:

• Human

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. Predicted to react with Rat and Bovine based on 100% sequence homology. View All» Application Notes: Western Blot Analysis: 0.5 µg/mLfrom a representative lot detected REM2 on 10 µg of human heart tissue lysate.Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected REM2 in NIH/3T3, A431, and HeLa cells. View All» Control: Human kidney tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human kidney tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected REM2 on 10 µg of human kidney tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8IYK8 View All» Entrez Gene Number: NP_775798 View All» Gene Symbol: REM2 View All» Alternate Names:
  • GTP-binding protein REM 2

  • Rad and Gem-like GTP-binding protein 2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry
      View All» Product Name: Anti-REM 2 (GTP-binding protein) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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