货号：ABD53

品牌：Merck Millipore

规格：100Ug

目录价：￥4899.00

市场价格：￥4164.15

会员价格：￥3919.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ZEB1 Antibody | Cat. No. ABD53 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~200 kDa observed. The calculated molecular weight is 124 kDa, however ZEB1 has been shown at ~180-210 kDa in western blots (Dave, N., et al. (2011). J. Biol. Chem. 286(14):12024-12032). View All» Epitope: 0 View All» Immunogen: KLH-conjugated linear peptide corresponding to human ZEB1. View All» Background Information: Zinc finger E-box-binding homeobox 1 (ZEB1), also known as Transcription factor 8 (TCF8) and Negative regulator of IL2 or NIL-2-A zinc finger protein is a member of the Zinc finger-Homeobox (ZFH)-family of repressors and acts as a transcriptional repressor that inhibits interleukin-2 (IL-2) gene expression. ZEB1 has also been implicated in regulating the expression of ATP1A1, E-cadherin, BCL6, and RCOR1 genes. ZEB1 regulates neurogenesis and neuronal differentiation, but is also implicated in tumor formation. ZEB1 is expressed in heart and skeletal muscle. Mutations in ZEB1 have been associated with corneal dystrophy. View All» Species Reactivity:

• Mouse

• Human

• Bovine

• Chicken

• Frog
  View All» Species Reactivity Note: Demonstrated to react with Mouse. Predicted to react with Bovine, Chicken, and Frog based on 100% sequence homology. Predicted to react with Human based on immunogen design. View All» Control: Mouse embryo e11 tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse embryo e11 tissue lysate.Western Blot Analysis: 1.0 µg/mL of this antibody detected ZEB1 in 10 µg of mouse embryo e11 tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P37275 View All» Entrez Gene Number: NP_110378 View All» Gene Symbol:
  • ZEB1

  • AREB6

  • TCF8
    View All» Alternate Names:
    • Zinc finger E-box-binding homeobox 1

    • NIL-2-A zinc finger protein

    • Negative regulator of IL2

    • Transcription factor 8

    • TCF-8
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Product Name: Anti-ZEB1 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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