货号:ABD74
品牌:Merck Millipore
规格:
目录价:¥4264.00
市场价格:¥3624.40
会员价格:¥3411.20
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Description:
Anti-HCFC1 Antibody | ABD74
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Molecular Weight:
~100 kDa observed. An uncharacterized band may be observed at ~33 kDa in some tissue lysates.
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Immunogen:
KLH-conjugated linear peptide corresponding to mouse HCFC1.
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Background Information:
Host cell factor 1 (HCFC1), also known as C1 factor or VCAF, is a collective name referring to a family of polypeptides derived from a 300 kDa transcriptional coactivator protein. The full length protein contains 5 kelch repeats, and is cleaved into at least twelve different functional polypeptides of varying molecular weights. These polypeptides have been implicated in mRNA processing, transcriptional coactivation, and cell-cycle progression. The full length HCFC1 is abundantly expressed in the liver, pituitary gland, skeletal muscle, eye, and brain. It is regulated by post-translational modifications, including O-glycosylation and ubiquitination. HCFC1 is processed by HCFC1R1, which results in the cytoplasmic localization of HCFC1. Previous studies have indicated that the HCFC1 may be an important switch between active and latent cycles of the herpes simplex virus.
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Species Reactivity:
Mouse
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Application Notes:
Immunohistochemistry Analysis: A representative lot of this antibody detected HCFC1 in normal mouse kidney and adrenal gland tissues.
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Control:
Mouse kidney tissue lysate
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Quality Assurance:
Evaluated by Western Blot in mouse kidney tissue lysate.Western Blot Analysis: 1 µg/mL of this antibody detected HCFC1 in 10 µg of mouse kidney tissue lysate.
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Purification Method:
Affinity purified
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Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
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Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
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UniProt Number:
Q61191
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Entrez Gene Number:
NP_032250
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Gene Symbol:
Hcfc1
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Alternate Names:
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Host cell factor 1
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HCF
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HCF-1
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C1 factor
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VCAF
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
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Western Blotting
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Immunohistochemistry (Paraffin)
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Product Name:
Anti-HCFC1
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Concentration:
1.0 mg/mL
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
100 μg
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Format:
Affinity Purified
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Host:
Rabbit
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