货号：ABE109

品牌：Merck Millipore

规格：100Ug

目录价：￥4068.00

市场价格：￥3457.80

会员价格：￥3254.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Pygopus homolog 2 Antibody | ABE109 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~50 kDa observed View All» Immunogen: KLH-conjugated linear peptide corresponding to human Pygopus homolog 2. View All» Background Information: Pygopus homolog 2 (PYGO2) is a member of the Pygopus protein family. Two mammalian Pygo genes (Pygo1 and Pygo) have been described. PYGO2 is an essential component of the canonical Wnt/beta-catenin transcriptional complex. This protein is often up regulated in malignant epithelial ovarian cancer cells and has been found to be widely expressed in other cancers such as breast cancer cells. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. View All» Application Notes: Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Pygopus homolog 2 in NIH/3T3, A431 and HeLa cells. View All» Control: HeLa nuclear extract View All» Quality Assurance: Evaluated by Western Blot in HeLa nuclear extract.Western Blot Analysis: 0.5 μg/mL of this antibody detected Pygopus homolog 2 on 10 µg of HeLa nuclear extract. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9BRQ0 View All» Entrez Gene Number: NP_612157.1 View All» Gene Symbol:
  • PYGO2

  • PP7910
    View All» Alternate Names:
    • Pygopus homolog 2

    • pygopus homolog 2

    • hPygo2

    • PYGO2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: Involved in signal transduction through the Wnt pathway.SUBUNIT STRUCTURE: Binds to BCL9 via the PHD-type zinc finger motif, and thereby becomes part of the nuclear beta-catenin/TCF complex.SUBCELLULAR LOCATION: Nucleus (probable). SEQUENCE SIMILARITIES: Contains 1 PHD-type zinc finger.SEQUENCE CAUTION: The sequence AAL55782.1 differs from that shown. Reason: Sequencing errors. View All» Product Name: Anti-Pygopus homolog 2 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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