Merck Millipore代理ABE203 Anti-JARID1D Antibody;store at +2℃ to +8℃

2025-06-27

货号:ABE203

品牌:Merck Millipore

规格:100Ug

目录价:¥5513.00

市场价格:¥4686.05

会员价格:¥4410.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-JARID1D Antibody | ABE203 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~174 kDa observed. Two isoforms may be observed due to alternative splicing at a molecular weight of ~167 kDa and ~174 kDa in some cell lysates. An uncharacterized band at a molecular weight of ~255 kDa may be observed in some cell lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human JARID1D. View All» Background Information: Also known as Lysine-specific demethylase 5D, this histone demethylase is specific for 'Lys-4' of histone H3 and is known to play a central role in histone function and spermatogenesis. It demethylates trimethylated and dimethylated, but not monomethylated H3 'Lys-4'. Uniprot.org states two different isoforms of this enzyme. View All» Species Reactivity:

  • Human

  • Mouse

    View All» Species Reactivity Note: Demonstrated to react with Human and Mouse. View All» Application Notes: Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected JARID1D in mESCs.Immunoprecipitation Analysis: A representative lot immunoprecipitated JARID1D in human testis tissue lysate. View All» Control: Human testis tissue lysate. View All» Quality Assurance: Evaluated by Western Blot in human testis tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected JARID1D in 10 µg of human testis tissue lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9BY66 View All» Entrez Gene Number: NP_004644.2 View All» Gene Symbol:
    • KDM5D

    • HY

    • HYA

    • JARID1D

    • KIAA0234

    • SMCY

      View All» Alternate Names:
      • Lysine-specific demethylase 5D

      • Histocompatibility Y antigen

      • H-Y

      • Histone demethylase JARID1D

      • Jumonji/ARID domain-containing protein 1D

      • Protein SmcY

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Western Blotting

        • Immunocytochemistry

        • Immunoprecipitation

          View All» Entrez Gene Summary: This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. View All» UniProt Summary: FUNCTION: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.COFACTOR: Ascorbate. Binds 1 Fe2+ ion per subunit.SUBUNIT STRUCTURE: Interacts with PCGF6 and MSH5.SUBCELLULAR LOCATION: Nucleus. View All» Product Name: Anti-JARID1D View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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