货号：ABE238

品牌：Merck Millipore

规格：100UL

目录价：￥4592.00

市场价格：￥3903.20

会员价格：￥3673.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Katanin-like 1 (KL1) Antibody | ABE238 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~55 kDa observed. Uncharacterized bands at ~210, 150, 63, and 45 may be observed in some lysates. View All» Immunogen: KLH-conjugated linear peptide corresponding to human KL1. View All» Background Information: Katanin-like 1 (KL1) is a mitotic regulator that is very closely related to katanin. KL1 is thought to be involved in microtubule severing because increased expression of KL1 leads to total disassembly of microtubules. KL1 is seen to localize to the spindle poles during mitosis, not to the centrosome. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Western Blot Analysis: A 1:1.000 dilution of this antibody detected KL1 on 10 µg of U2OS cell lysate.Immunocytochemistry: A representative lot of this antibody was used for IC by an independent laboratory (Sonbuchner, T.M., et al. (2010). Cell Cycle. 9(12):2403-2411). View All» Control: HeLa cell lysate View All» Quality Assurance: Evaluated by Western Blot in HeLa cell lysate.Western Blot Analysis: A 1:1.000 dilution of this antibody detected KL1 on 10 µg of HeLa cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9BW62 View All» Entrez Gene Number: NP_001014402 View All» Gene Symbol: KATNAL1 View All» Alternate Names:

• Katanin p60 ATPase-containing subunit A-like 1

• Katanin p60 subunit A-like 1

• p60 katanin-like 1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays (By similarity).CATALYTIC ACTIVITY: ATP + H2O = ADP + phosphate.SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton (By similarity). SEQUENCE SIMILARITIES: Belongs to the AAA ATPase family. View All» Product Name: Anti-Katanin-like 1 (KL1) View All» Concentration: 0.43 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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