金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: HM74A/PUMA-G/GPR109A Long Name: G Protein-coupled Receptor HM74A/G Protein-coupled Receptor 109A Aliases: GPR109A; HCA2; HCAR2; Niacr1; Nicotinic Acid Receptor; PUMAG Entrez Gene IDs: 338442 (Human); 80885 (Mouse) Background: HM74A/GPR109A The low affinity and high affinity receptors for nicotinic acid (niacin) are the inhibitory G-protein coupled receptors HM74/GPR109B and HM74A/GPR109A, respectively. Binding of niacin to HM74A mediates an anti-lipolytic effect observed on adipose tissue. HM74A is also expressed on mouse splenocytes, as niacin and other vitamins can enhance the mitogenic response of lymphocytes.