货号：ABE395

品牌：Merck Millipore

规格：EA

目录价：￥3708.00

市场价格：￥3151.80

会员价格：￥2966.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Elongator complex protein 3 Antibody | ABE395 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody may recognize both isoforms of Elongator complex protein 3. View All» Molecular Weight: ~60 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing with MW ~62 & 60KDa. This antibody may recognize both isoforms. View All» Immunogen: KLH-conjugated linear peptide corresponding to human Elongator complex protein 3. View All» Background Information: Elongator complex protein 3 is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex (Elongator), which is involved in transcriptional elongation. Elongator plays a role in chromatin remodeling and is involved in acetylation of histones H3 and H4. Elongator has also been implicated in methyltransferase activity, however, most Elongator is cytoplasmic, and recent data has indicated a role in processes such as exocytosis and tRNA modification. Elongator complex protein 3 is encoded by a gene that is mutated in patients suffering from the severe neurodevelopmental disorder familial dysautonomia. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Rhesus Macaque, and Chimpanzee based on 100% sequence homology. View All» Application Notes: Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Elongator complex protein 3 in normal human kidney tissue. View All» Control: K562 lysate View All» Quality Assurance: Evaluated by Immunoprecipitation in K562 lysate.Immunoprecipitation Analysis: 10 µg of this antibody immunoprecipitated Elongator complex protein 3 from 0.5 mg of K562 lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9H9T3 View All» Entrez Gene Number: NP_060561 View All» Gene Symbol: ELP3 View All» Alternate Names: hELP3 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Immunoprecipitation

• Immunohistochemistry (Paraffin)
  View All» Product Name: Anti-Elongator complex protein 3 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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