货号：ABE404

品牌：Merck Millipore

规格：EA

目录价：￥3708.00

市场价格：￥3151.80

会员价格：￥2966.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Dnmt2 Antibody | ABE404 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody will only recognize isoforms A, B, and C of Dnmt2. View All» Molecular Weight: ~44 kDa and ~40 kDa observed. Uniprot reports 6 isoforms for Dnmt2. This antibody will only recognize isoforms A, B, and C. View All» Immunogen: KLH-conjugated linear peptide corresponding to human Dnmt2. View All» Background Information: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression and genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with Human. View All» Application Notes: Immunohistochemistry Analysis: A 1:1,000 dilution of a representative lot detected Dnmt2 in human placenta and human pancreatic tissues. View All» Control: MCF7 cell lysate View All» Quality Assurance: Evaluated by Western Blot in MCF7 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected Dnmt2 in 10 µg of MCF7 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: O14717 View All» Entrez Gene Number: NP_004403 View All» Gene Symbol:

• TRDMT1

• DNMT2
  View All» Alternate Names: tRNA (cytosine(38)-C(5))-methyltransferaseDNA (cytosine-5)-methyltransferase-like protein 2DNA methyltransferase homolog HsaIIPDNA MTase homolog HsaIIPM.HsaIIP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Western Blotting
    View All» Product Name: Anti-Dnmt2 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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